Cells generate diverse microtubule populations by polymerization of a common alpha/beta-tubulin building block.How microtubule associated proteins translate microtubule heterogeneity into specific cellular functions is not clear.We evaluated the ability of kinesin motors involved in vesicle transport to read microtubule heterogeneity by using singl

Keratinocytes are the first cells that come into direct contact with external tactile stimuli; however, their role in touch transduction in vivo is not clear.The ion channel Transient Receptor Potential Ankyrin 1 (TRPA1) is essential for some mechanically-gated currents SPRING LOADED FRIZZ FIGHTING in sensory neurons, amplifies mechanical responses

Introduction: Traditionally, ventilatory mechanics has been delivered in controlled modes through the use of inappropriate approaches for spontaneous ventilation.Objective: To measure the changes of ventilatory mechanics caused by PEEP and pressure support (PS) variations in non-invasive mechanical ventilation.Materials and methods: The ventilatory

In order to study the flutter of long-span pedestrian suspension bridge and its aerodynamic control, a 420m-span pedestrian suspension bridge is used as an engineering example, the wind-induced vibration of seven particular aerodynamic sections is studied by wind tunnel tests, and the soft flutter phenomenon of two kinds of aerodynamic sections is

This paper studies the short-term impacts of air pollutants on mortality rates in a range of diseases including cardiovascular, respiratory and Cat Dehydrated digestive diseases, tumors and cancers.It uses daily data of suspended particulate matters (SPM), CO, NOx, and O3 in six metropolitan areas of Tehran, Ahvaz, Mashhad, Tabriz, Shiraz, and Esfa